PHILADELPHIA -- Darren Sproles had two touchdowns, Mark Sanchez threw for two scores and the defense sacked Cam Newton nine times to help the Philadelphia Eagles beat the Carolina Panthers 45-21 Monday night.

Filling in for an injured Nick Foles, Sanchez had 332 yards passing in his first start since Dec. 30, 2012. Sproles returned a punt 65 yards for a score and had an 8-yard TD run. Bradley Fletcher returned an interception 34 yards for a TD and Jordan Matthews had 138 yards receiving and two TDs.

The Eagles (7-2) stayed on top in the NFC East. They're trying to repeat as division champions without Foles, who broke his collarbone in a win at Houston last week.

The Panthers (3-6-1) hardly look like the team that won the NFC South last year.