The Philadelphia Eagles tied the game with just over six minutes remaining and never got the ball back as the Los Angeles Chargers kicked a field goal with two seconds left to win 27-24.
The Eagles rushed for more than 200 yards and four touchdowns. They also sacked Jared Goff six times and scored a defensive touchdown. It led to a dominating 44-6 victory over the winless Detroit Lions.
Former Eagles assistant coach Ryan Paganetti chose two matchups that he thinks will determine whether the Eagles can start the year 2-0 or whether it will be the 49ers who get off to a 2-0 start.
ESPN.com asked more than 50 league executives, coaches, scouts and players to help rank the top 10 players at 11 different positions, including cornerback.
Wednesday's Football at Four: Geoff Mosher talks Darius Slay recruiting Steven Nelson, latest on Zach Ertz, reaction to Doug Pederson's comments, and more