The Philadelphia Eagles will be without some key weapons for Sunday’s home game against the Indianapolis Colts.  The team has ruled running backs Jay Ajayi and Darren Sproles out for the game, additional Alshon Jeffery will not play in the game, even though he is listed as questionable, he hasn't been cleared for contact.

Sproles did not play last week in the Eagles’ loss to the Tampa Bay Buccaneers due to a hamstring injury. He missed practice on Wednesday and Thursday. The 35-year-old is playing in his final season after missing most of last season with a torn ACL and a broken arm.

Corey Clement, who is listed as questionable with a quad injury, should see an increased work-load on Sunday, with Wendell Smallwood and Josh Adams also in the mix. Clement is a former rookie free agent out of Wisconsin and has 11 carries for 56 yards in two games this season.

Ajayi is dealing with a back injury, that he suffered last week in Tampa.  He left the game in the first half, but returned to the game in the second half, but did not practice on Wednesday, Thursday and Friday. He is currently leads the Eagles with 22 carries, 85 yards and three touchdowns.

In addition to Clement and Jeffery, left tackle Jason Peters and linebacker Kamu Grugier-Hill are listed as questionable.

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