Eagles running back Miles Sanders had to leave Sunday's game against the Giants with a hand injury and did not return.

Now it appears the injury could force him to miss the rest of the regular season and some of the playoffs, should the Eagles qualify with what the teams fears is a fractured hand.

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He was seen on the sidelines with his hand heavily bandaged during the game after he was ruled out.

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Mike Florio of NBC Sports and ProFootballTalk.com said on the Sunday Night Football game pregame said that Sanders suffered a fractured hand in Week 16 against the Giants.

On Monday, Eagles head coach Nick Sirianni confirmed that report.

"Miles did break his hand and, obviously, he'll be out this week and then we will re-evaluate after a week," Sirianni stated. "We are hopeful we can get him back at some point this season, so he will not be going to IR."

The Eagles are no stranger to Sanders missing time, he has played in 11 of 15 games this season, running for 709 yards and 5.5 yards per carry.

With Sanders out, the team will again turn to Jordan Howard, Boston Scott, and Kenny Gainwell, though Howard had to leave the game in the fourth quarter with what is being called a stinger and did not return.

"MRI came back good and we're hopeful," Sirianni said about Howard's injury. "I'm not going to put any timetables on anybody, but we're hopeful for Jordan."

Update: NFL Network's Ian Rapoport reports the Eagles running back MIles Sanders will have an MRI on his broken hand "to determine if there is other damage and whether or not he can play through it."

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